Clinical Trials Manager ©

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  Updated 05/13/2008 8:25:56

Trial status: Active

Trials found: 531

Clinical Trials Network : Therapeutic group
Cardiovascular
Liver Disease
Neurology

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Trial details


Clinical Trials Network
Group : Cardiovascular
ACCOMPLISH - Prospective, multinational, multicenter, double-blind, randomized, active-controlled, trial to compare effects of Lotrel to benazepril & hydrochlorothiazide combined on reduction of cardiovascular morbidity & morality patients w/ high risk hy
 
Principal Investigator: Mathew Maurer  
Start date: 03/24/2004
End date: 12/24/2009
to request information from Principal Investigator.
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ACCORD - N01 HC 95184/Action to Control Cardiovascular Risk in Diabetes
 
Principal Investigator: J. Thomas Bigger, Jr.  
Website: www.accord-ne.org
Start date: 09/30/1999
End date: 04/30/2010
to request information from Principal Investigator.
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ACCORD-Eye - Action to Control Cardiovascular Risk in Diabetes -- Eye Substudy
 
Principal Investigator: J. Thomas Bigger, Jr.  
Website: www.accord-ne.org
Start date: 11/01/2003
End date: 04/30/2010
to request information from Principal Investigator.
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Clinical Trials Network
Group : Liver Disease
GI262570 - Double-Blind, Randomized, Placebo-Controlled Multi-Center, Phase II Parallel Dose-Ranging Study to Assess the Antifibrotic Activity of GI262570 in Chronic Hepatitis C Subjects with Hepatic Fibrosis who Have Failed Prior Antiviral Therapy.
 
Principal Investigator: Robert S. Brown  
Start date: 05/01/2006
End date: 11/30/2008
to request information from Principal Investigator.
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Infergen Trial - Efficacy and Safety of Daily Infergen/Ribavirin in Patients with Chronic Hepatitis C Virus Genotype 1Invection Who Were Partial Responders after Peginterferon alfa/Ribavirin Therapy
 
Principal Investigator: Robert S. Brown  
Start date: 06/13/2007
End date: 12/31/2008
to request information from Principal Investigator.
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Clinical Trials Network
Group : Neurology
Closure 1 - PROSPECTIVE, MULTICENTER, RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF THE STARFlex® SEPTAL CLOSURE SYSTEM VERSUS BEST MEDICAL THERAPY IN PATIENTS WITH A STROKE AND/OR TRANSIENT ISCHEMIC ATTACK DUE TO PRESUMED PARADOXICAL
 
Principal Investigator: Clinton Wright  
Start date: 08/09/2007
End date: 06/30/2009
to request information from Principal Investigator.
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Department :Anesthesiology
Division : Intensive Care Units
Association between protein C levels and morbidity following liver tranplant
 
Principal Investigator: Robert N. Sladen  
Start date: 11/15/2006
End date: 05/31/2008
to request information from Principal Investigator.
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ECLIPSE-NIC - Evaluation of Clevelox In the Postoperative Treatment of Hypertension Assessing Safety Events (with Nicardipine as Active Comparator)
 
Principal Investigator: Robert N. Sladen  
Start date: 09/10/2004
End date: 06/30/2008
to request information from Principal Investigator.
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Efficacy of the Kimberly-Clark Warming System in Preventing Temperature Pertubations Following Cardiac Surgery with Cardiopulmonary Bypass
 
Principal Investigator: Robert N. Sladen  
Start date: 02/22/2006
End date: 10/02/2008
to request information from Principal Investigator.
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Multicenter, double-blind, randomized, placebo-controlled, parallel-group study to assess the efficacy, safety and tolerability of tezosentan in patients with preoperative pulmonary hypertension, due to left heart disease, undergoing cardiac surgery
 
Principal Investigator: Ervant Nishanian  
Start date: 07/30/2007
End date: 06/12/2008
to request information from Principal Investigator.
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Department :Dermatology
Division : Cosmetic Dermatology
Early Diagnosis of Melanoma - Early Diagnosis of Melanoma Using Expression Profiling and Non-Invasive Sampling of Skin Cells.
 
Principal Investigator: Julide T Celebi  
Start date: 04/10/2008
End date: 10/31/2009
to request information from Principal Investigator.
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Department :Dermatology
Division : Dermatology Clinic
Nitrogen Mustard 0.04% - Open Label Six Month Study to Evaluate the Safety and Efficacy of Nitrogen Mustard (NM) 0.04% Ointment Formulation in Patients with Stage I or IIA Mycosis Fungoides (MF) Who Have Completed an Initial 12 Month Treatment with Nitrog
 
Principal Investigator: Elizabeth Knobler  
Start date: 02/14/2008
End date: 09/30/2009
to request information from Principal Investigator.
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Phase II Pivotal Trial to Evaluate the Safety and Efficacy of Nitrogen Mustard (NM) 0.02% Ointment Formulations in Patients with Stage I or IIA Mycosis Fungoides (MF)
 
Principal Investigator: Elizabeth Knobler  
Start date: 06/12/2007
End date: 12/31/2009
to request information from Principal Investigator.
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Department :Dermatology
Division : General Practice
ABT-874 in Psoriasis - Phase 3, Multicenter, Randomized, Double-blind, Placebo-Controlled Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects with Moderate to Severe Chronic Plaque Psoriasis
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 02/29/2008
End date: 08/31/2009
to request information from Principal Investigator.
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An Un-blinded Exploratory Study to Evaluate a Cutaneous Incisional Wound Model of Mast Cell Infiltration in Healthy Volunteers and Idiopathic Pulmonary Fibrosis (IPF) Patients
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 12/13/2007
End date: 06/30/2010
to request information from Principal Investigator.
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Observational Post-marketing Safety Surveillance Registry of Enbrel (etanercept) for Treatment of Psoriasis
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 07/20/2006
End date: 02/28/2016
to request information from Principal Investigator.
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Open Label Efficacy and Safety Study of Amevive (alfacept) in Patients with moderate to sever Chronic plaque Psoriasis with Nail Involvement
 
Principal Investigator: Richard K. Scher  
Start date: 12/11/2004
End date: 08/06/2008
to request information from Principal Investigator.
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PHASE II TRIAL OF THE SAFETY, LOCAL TOLERABILITY, AND EFFICACY OF CHRONIC DAILY UNGUAL APPLICATION OF ECONAIL (ECON AZOLE 5% SEPA 18% NAIL LACQUER) TO SUBJECT WITH ONYCHOMYCOSIS OF THE TOENAIL
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 07/07/2006
End date: 02/28/2009
to request information from Principal Investigator.
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Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of BID Application of Tacrolimus Cream-B 0.1% Vs. Cream Vehicle in the Treatment of Psoriasis
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 12/05/2005
End date: 06/30/2008
to request information from Principal Investigator.
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Phase III Randomized, Evaluator-Blind, Parallel Group Study of the Safety and Efficacy of Itraconazole Tablets, Itraconazole Capsules and Placebo in the Treatment of Onychomycosis of the Toenail
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 05/11/2007
End date: 11/30/2010
to request information from Principal Investigator.
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Randomized, double-blind, vehicle-controlled, multicenter, parallel group study to assess the efficacy, safety, & tolerability of topical terbinafine HCl for 24 or 48 weeks of treatment in patients with mild to moderate toenail onychomycosis
 
Principal Investigator: Julian Mackay-Wiggan  
Start date: 11/15/2006
End date: 05/31/2009
to request information from Principal Investigator.
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Single Center, Open-Label, Efficacy and Safety of Tazarotene for the Treatment of Brittle Nails
 
Principal Investigator: Richard K. Scher  
Start date: 11/12/2004
End date: 05/31/2008
to request information from Principal Investigator.
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Department :Dermatology
Division : Other
Chemoprevention of Basal Cell Carcinomas with Tazarotene
 
Principal Investigator: David R. Bickers  
Start date: 07/01/2007
End date: 06/30/2008
to request information from Principal Investigator.
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Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of a subcutaneous formulation fo Icatibant for the treatment of Hereditary Angioedema
 
Principal Investigator: David J Resnick  
Website: landerson@inclin.com
Start date: 11/01/2005
End date: 05/31/2008
to request information from Principal Investigator.
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Department :Dermatology
Division : Pediatrics
APPLES - Prospective Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Tacrolimus Ointment for the Treatment of Atopic Dermatitis
 
Principal Investigator: Kimberly D. Morel  
Start date: 11/22/2005
End date: 09/30/2020
to request information from Principal Investigator.
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Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study of the Safety and Efficacy of Thymosin Beta 4 in the Treatment of Patients with Epidermolysis Bullosa
 
Principal Investigator: Kimberly D. Morel  
Start date: 01/19/2006
End date: 07/31/2008
to request information from Principal Investigator.
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Department :Medicine
Division : Cardiology
ACROSS CYPHER - Approaches to Chronic Occlusions with Sirolimus Stents
 
Principal Investigator: Jeffrey W. Moses  
Start date: 05/09/2005
End date: 11/30/2008
to request information from Principal Investigator.
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ARVD - Multidisciplinary Study of Right Ventricular Dysplasia ARVD study (Yr 1)
 
Principal Investigator: Hasan Garan  
Start date: 08/01/2005
End date: 07/31/2008
to request information from Principal Investigator.
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Angioguard - Carotid Artery Stenting with Embolic Protection Surveillance-Post Marketing Study
 
Principal Investigator: Issam D. Moussa  
Start date: 06/02/2005
End date: 11/30/2008
to request information from Principal Investigator.
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Assessment of Antibodies to Adeno-Associated Vector Type 1 in Patients with Heart Failure
 
Principal Investigator: Donna Mancini  
Start date: 03/08/2007
End date: 09/30/2008
to request information from Principal Investigator.
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CAPTURE 2 - CAPTURE 2: A POST-APPROVAL STUDY OF THE GUIDANT CAROTID STENT SYSTEMS AND EMBOLIC PROTECTION SYSTEMS
 
Principal Investigator: Issam D. Moussa  
Start date: 04/06/2006
End date: 06/30/2008
to request information from Principal Investigator.
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CHAMPION - Clinical Trial Comparing Cangrelor to Clopidogrel in Subjects who Require Percutaneous Coronary Intervention
 
Principal Investigator: George Dangas  
Start date: 04/24/2008
End date: 10/31/2010
to request information from Principal Investigator.
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CHOICE - CHOICE Study - Carotid Stenting For High Surgical-Risk Patients; Evaluating Outcomes Through The Collection Of Clinical Evidence.
 
Principal Investigator: William Gray  
Start date: 02/28/2008
End date: 08/31/2009
to request information from Principal Investigator.
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COSTAR II - Cobalt Chromium Stent with Antiproliferative for Restenosis II Trial
 
Principal Investigator: Michael Collins  
Website: unknown
Start date: 06/08/2005
End date: 12/31/2009
to request information from Principal Investigator.
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CUPID Trial - Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease
 
Principal Investigator: Donna Mancini  
Start date: 05/04/2007
End date: 11/30/2012
to request information from Principal Investigator.
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Carotid DVA
 
Principal Investigator: Issam D. Moussa  
Start date: 01/27/2006
End date: 07/31/2009
to request information from Principal Investigator.
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Complete SE Registry - Complete SE Registry: Percutaneous interventional treatment of iliac artery lesions using the Medtronic Complete® Self-Expanding (SE) Iliac Stent.
 
Principal Investigator: William Gray  
Start date: 04/15/2008
End date: 10/31/2010
to request information from Principal Investigator.
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Cryo Cath - Cryocath Frezzor Cryo Ablation Catheter System
 
Principal Investigator: Hasan Garan  
Start date: 02/07/2007
End date: 08/31/2009
to request information from Principal Investigator.
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Double-blind, prospective, randomized, placebo-controlled study to determine the tolerability, efficacy, safety, and dose range of intramyocardial injections of G-CSF mobilized Auto-CD34+ cells for reduction of angina episodes in pts with refractory
 
Principal Investigator: Warren Sherman  
Start date: 08/14/2006
End date: 02/28/2011
to request information from Principal Investigator.
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EMPIRE - Embolic Protection with Reverse Flow Study of the Gore Neuro Protection System in Carotid Stenting of Subjects at High Risk for Carotid Endarterectomy
 
Principal Investigator: William Gray  
Start date: 10/08/2007
End date: 03/31/2010
to request information from Principal Investigator.
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ENDEAVOR 4 - Randomized, controlled trial of the medtronic endeavor drug(ABT-578) eluting coronary stent system vs. the Taxus Paclitaxel-eluting coronary stent system in de novo native coronary lesions
 
Principal Investigator: Jeffrey W. Moses  
Start date: 05/12/2005
End date: 11/30/2010
to request information from Principal Investigator.
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EVEREST I - Study of the EvalveÔ Cardiovascular Valve Repair System (CVRS) Endovascular Valve Edge-to-Edge REpair STudy
 
Principal Investigator: William Gray  
Start date: 04/08/2004
End date: 07/31/2008
to request information from Principal Investigator.
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EVEREST II - Study of the Evalve Cardiovascular Valve repair system (CVRS) endovascular valve edge-to-edge repair study
 
Principal Investigator: William Gray  
Start date: 03/21/2005
End date: 09/30/2009
to request information from Principal Investigator.
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EXACT
 
Principal Investigator: Issam D. Moussa  
Start date: 07/31/2006
End date: 02/28/2009
to request information from Principal Investigator.
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Escape - Effect of Septal Closure of Atrial PFO on Events of Migraine with the Premere Device Escape Migraine Trial
 
Principal Investigator: Robert Sommer  
Start date: 02/13/2006
End date: 08/31/2008
to request information from Principal Investigator.
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Lipoprotein Utilization and Oxidation in CHF
 
Principal Investigator: Ulrich P Jorde  
Start date: 07/01/2007
End date: 06/30/2008
to request information from Principal Investigator.
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MGH OFDI - MGH OFDI: Natural History of Vulnerable Coronary Plaques
 
Principal Investigator: Martin Leon  
Start date: 08/01/2007
End date: 03/31/2009
to request information from Principal Investigator.
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MOMENTUM - Multicenter trial of the Orqis Medical CRS for the Enhanced Treatment of CHF Unresponsive to Medical Therapy
 
Principal Investigator: Donna Mancini  
Start date: 02/24/2006
End date: 08/31/2008
to request information from Principal Investigator.
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MYOHEART - Myogenesis Heart Efficiency and Regeneration Trial
 
Principal Investigator: Warren Sherman  
Start date: 07/11/2006
End date: 01/31/2012
to request information from Principal Investigator.
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MediGuide Trial - MediGuide Trial: Medical Positioning System (MPS) In Conjunction with Guided Measurement Catheter (GMC™) Feasibility Study in Clinical Routine.
 
Principal Investigator: Giora Weisz  
Start date: 03/09/2008
End date: 09/30/2009
to request information from Principal Investigator.
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Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Effects of KW-3902 Injectable Emulsion on Heart Failure Signs and Symptoms, Diuresis, Renal Function, and Clinical Outcomes in Subjects Hospitalized with Worsening Renal Function
 
Principal Investigator: Paolo C. Colombo  
Start date: 12/19/2007
End date: 07/31/2011
to request information from Principal Investigator.
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Multicenter, Single Arm Study of the TAxus Liberte Stent for the Treatment of Patients with DeNovo Coronary Artery Lesions in Small Vessels
 
Principal Investigator: Donna Mancini  
Start date: 08/02/2006
End date: 02/28/2009
to request information from Principal Investigator.
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Optivol Study - Correlation Between T Wave Alternans and Intrathoracic Impedance Measurements Using Optivol T Wave Alternans/Optivol Study.
 
Principal Investigator: Jose Dizon  
Start date: 04/28/2007
End date: 10/31/2010
to request information from Principal Investigator.
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PARTNER - The PARTNER Trial: Placement of Aortic Transcatheter Valves Trial
 
Principal Investigator: Martin Leon  
Start date: 05/29/2007
End date: 11/30/2009
to request information from Principal Investigator.
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PROTECT-II - multicenter, randomized, double-blind, placebo-controlled study of the effects of KW-3902 Injectable Emulsion on heart failure signs and symptoms and renal function in subjects with acute heart failure signs and renal impairment who are hospi
 
Principal Investigator: Maryjane A. Farr  
Start date: 02/14/2008
End date: 09/30/2010
to request information from Principal Investigator.
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Perseus Trial - Perseus Trial: A Prospective Evaluation in a Non-Randomized Trial of the Safety and Efficacy of the Use of the TAXUS[r] ElementTM Paclitaxel-Eluting Coronary Stent System for the Treatment of De Novo Coronary Artery Lesions in Small Vesse
 
Principal Investigator: Jeffrey W. Moses  
Start date: 01/28/2008
End date: 08/31/2013
to request information from Principal Investigator.
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Perseus Workhorse Trial - Perseus WorkhorseTrial: A Prospective Evaluation in a Non-Randomized of the Safety and Efficacy of the Use of the TAXUS (R) ElementTM Paclitaxel-Eluting Coronary Stent System for the Treatment of De Novo Coronary Artery Lesions i
 
Principal Investigator: Jeffrey W. Moses  
Start date: 01/28/2008
End date: 08/31/2013
to request information from Principal Investigator.
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Power Disc-15 - Comparison of Safety and Inhalation Times of Ventavis (iloprost) Inhalation Solution Delivered by I-Neb Utilizing Power Disc-6 and Power Disc-15
 
Principal Investigator: Evelyn M Horn  
Start date: 06/19/2007
End date: 12/31/2009
to request information from Principal Investigator.
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Protect II (IMPELLA) - PROTECT II: A Prospective, multi-center randomized controlled trial of the IMPELLA® RECOVER® LP 2.5 System versus Intra Aortic Balloon Pump (IABP) in Patients Undergoing Non-Emergent High Risk PCI
 
Principal Investigator: Michael Collins  
Start date: 04/10/2008
End date: 10/31/2009
to request information from Principal Investigator.
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RECORDAF - Registry on Cardiac Rhythm Disorders: An International, Observational, Prospective Survey Assessing the Control of Atrial Fibrillation.
 
Principal Investigator: James A. Reiffel  
Start date: 01/16/2008
End date: 07/31/2009