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Contact webmaster   Updated 05/13/2008 8:25:56 Trial status: Active Trials found: 531 Clinical Trials Network : Therapeutic group Cardiovascular Liver Disease Neurology Department Division Anesthesiology Intensive Care Units Dermatology Cosmetic Dermatology Dermatology Clinic General Practice Other Pediatrics Medicine Cardiology Circulatory Physiology Digestive & Liver Diseases Endocrinology General Medicine Hematology and Oncology Infectious Diseases Medical Oncology Naomi Berrie Diabetes Center Nephrology Preventive Medicine & Nutrition Pulmonary Cardiology Pulmonary, Allergy & Critical Care Medicine Rheumatology Neurological Surgery Epilepsy Movement Neuro Surgeon Neurooncology Spine Neurology Dementia and Aging Epilepsy G H Sergievsky Center General Neurology Movement Disorders Movement Disorders/neuromuscular Multiple Sclerosis and Demyelinating Diseases Neuro-critical Care Neuromuscular Disease Neurooncology Stroke and Critical Care Obstetrics and Gynecology Family Planning Gynecologic Oncology Maternal Fetal Medicine Menopause Obstetrics and Gynecology Reproduction and Endocrinology Ophthalmology Glaucoma Macula Surgical & Medical Retinal Disease Ophthalmology Other Orthopedic Surgery Lower Extremity and Reconstruction Pathology Gynecological Pathology Hemopathology Perinatal/developmental Pathology Pediatrics Autoimmune & Molecular Diseases Cardiology Endocrinology Gastroenterology & Nutrition Hematology and Blood and Marrow Transplant Infectious Diseases Molecular Genetics Neonatology & Perinatal Medicine Nephrology Oncology Pulmonary Rheumatology Psychiatry Behavioral Medicine Child Psychiatry Neuroscience Other Substance Abuse Therapeutics - Administration Therapeutics - Anxiety Clinic Therapeutics - Depression Evaluation Radiation Oncology Radiation Oncology Radiology Interventional Radiology Neurosurgery Nuclear Medicine Surgery Cardiothoracic Surgery Center For Liver Disease & Transplantation Other Surgical Oncology Surgical Specialties Vascular Surgery Urology Bph Incontinence Oncology Trial details Clinical Trials Network Group : Cardiovascular ACCOMPLISH - Prospective, multinational, multicenter, double-blind, randomized, active-controlled, trial to compare effects of Lotrel to benazepril & hydrochlorothiazide combined on reduction of cardiovascular morbidity & morality patients w/ high risk hy   Principal Investigator: Mathew Maurer   Start date: 03/24/2004 End date: 12/24/2009 to request information from Principal Investigator.    Top of page ACCORD - N01 HC 95184/Action to Control Cardiovascular Risk in Diabetes   Principal Investigator: J. Thomas Bigger, Jr.   Website: www.accord-ne.org Start date: 09/30/1999 End date: 04/30/2010 to request information from Principal Investigator.    Top of page ACCORD-Eye - Action to Control Cardiovascular Risk in Diabetes -- Eye Substudy   Principal Investigator: J. Thomas Bigger, Jr.   Website: www.accord-ne.org Start date: 11/01/2003 End date: 04/30/2010 to request information from Principal Investigator.    Top of page Clinical Trials Network Group : Liver Disease GI262570 - Double-Blind, Randomized, Placebo-Controlled Multi-Center, Phase II Parallel Dose-Ranging Study to Assess the Antifibrotic Activity of GI262570 in Chronic Hepatitis C Subjects with Hepatic Fibrosis who Have Failed Prior Antiviral Therapy.   Principal Investigator: Robert S. Brown   Start date: 05/01/2006 End date: 11/30/2008 to request information from Principal Investigator.    Top of page Infergen Trial - Efficacy and Safety of Daily Infergen/Ribavirin in Patients with Chronic Hepatitis C Virus Genotype 1Invection Who Were Partial Responders after Peginterferon alfa/Ribavirin Therapy   Principal Investigator: Robert S. Brown   Start date: 06/13/2007 End date: 12/31/2008 to request information from Principal Investigator.    Top of page Clinical Trials Network Group : Neurology Closure 1 - PROSPECTIVE, MULTICENTER, RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF THE STARFlex® SEPTAL CLOSURE SYSTEM VERSUS BEST MEDICAL THERAPY IN PATIENTS WITH A STROKE AND/OR TRANSIENT ISCHEMIC ATTACK DUE TO PRESUMED PARADOXICAL   Principal Investigator: Clinton Wright   Start date: 08/09/2007 End date: 06/30/2009 to request information from Principal Investigator.    Top of page Department : Anesthesiology Division : Intensive Care Units Association between protein C levels and morbidity following liver tranplant   Principal Investigator: Robert N. Sladen   Start date: 11/15/2006 End date: 05/31/2008 to request information from Principal Investigator.    Top of page ECLIPSE-NIC - Evaluation of Clevelox In the Postoperative Treatment of Hypertension Assessing Safety Events (with Nicardipine as Active Comparator)   Principal Investigator: Robert N. Sladen   Start date: 09/10/2004 End date: 06/30/2008 to request information from Principal Investigator.    Top of page Efficacy of the Kimberly-Clark Warming System in Preventing Temperature Pertubations Following Cardiac Surgery with Cardiopulmonary Bypass   Principal Investigator: Robert N. Sladen   Start date: 02/22/2006 End date: 10/02/2008 to request information from Principal Investigator.    Top of page Multicenter, double-blind, randomized, placebo-controlled, parallel-group study to assess the efficacy, safety and tolerability of tezosentan in patients with preoperative pulmonary hypertension, due to left heart disease, undergoing cardiac surgery   Principal Investigator: Ervant Nishanian   Start date: 07/30/2007 End date: 06/12/2008 to request information from Principal Investigator.    Top of page Department : Dermatology Division : Cosmetic Dermatology Early Diagnosis of Melanoma - Early Diagnosis of Melanoma Using Expression Profiling and Non-Invasive Sampling of Skin Cells.   Principal Investigator: Julide T Celebi   Start date: 04/10/2008 End date: 10/31/2009 to request information from Principal Investigator.    Top of page Department : Dermatology Division : Dermatology Clinic Nitrogen Mustard 0.04% - Open Label Six Month Study to Evaluate the Safety and Efficacy of Nitrogen Mustard (NM) 0.04% Ointment Formulation in Patients with Stage I or IIA Mycosis Fungoides (MF) Who Have Completed an Initial 12 Month Treatment with Nitrog   Principal Investigator: Elizabeth Knobler   Start date: 02/14/2008 End date: 09/30/2009 to request information from Principal Investigator.    Top of page Phase II Pivotal Trial to Evaluate the Safety and Efficacy of Nitrogen Mustard (NM) 0.02% Ointment Formulations in Patients with Stage I or IIA Mycosis Fungoides (MF)   Principal Investigator: Elizabeth Knobler   Start date: 06/12/2007 End date: 12/31/2009 to request information from Principal Investigator.    Top of page Department : Dermatology Division : General Practice ABT-874 in Psoriasis - Phase 3, Multicenter, Randomized, Double-blind, Placebo-Controlled Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects with Moderate to Severe Chronic Plaque Psoriasis   Principal Investigator: Julian Mackay-Wiggan   Start date: 02/29/2008 End date: 08/31/2009 to request information from Principal Investigator.    Top of page An Un-blinded Exploratory Study to Evaluate a Cutaneous Incisional Wound Model of Mast Cell Infiltration in Healthy Volunteers and Idiopathic Pulmonary Fibrosis (IPF) Patients   Principal Investigator: Julian Mackay-Wiggan   Start date: 12/13/2007 End date: 06/30/2010 to request information from Principal Investigator.    Top of page Observational Post-marketing Safety Surveillance Registry of Enbrel (etanercept) for Treatment of Psoriasis   Principal Investigator: Julian Mackay-Wiggan   Start date: 07/20/2006 End date: 02/28/2016 to request information from Principal Investigator.    Top of page Open Label Efficacy and Safety Study of Amevive (alfacept) in Patients with moderate to sever Chronic plaque Psoriasis with Nail Involvement   Principal Investigator: Richard K. Scher   Start date: 12/11/2004 End date: 08/06/2008 to request information from Principal Investigator.    Top of page PHASE II TRIAL OF THE SAFETY, LOCAL TOLERABILITY, AND EFFICACY OF CHRONIC DAILY UNGUAL APPLICATION OF ECONAIL (ECON AZOLE 5% SEPA 18% NAIL LACQUER) TO SUBJECT WITH ONYCHOMYCOSIS OF THE TOENAIL   Principal Investigator: Julian Mackay-Wiggan   Start date: 07/07/2006 End date: 02/28/2009 to request information from Principal Investigator.    Top of page Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of BID Application of Tacrolimus Cream-B 0.1% Vs. Cream Vehicle in the Treatment of Psoriasis   Principal Investigator: Julian Mackay-Wiggan   Start date: 12/05/2005 End date: 06/30/2008 to request information from Principal Investigator.    Top of page Phase III Randomized, Evaluator-Blind, Parallel Group Study of the Safety and Efficacy of Itraconazole Tablets, Itraconazole Capsules and Placebo in the Treatment of Onychomycosis of the Toenail   Principal Investigator: Julian Mackay-Wiggan   Start date: 05/11/2007 End date: 11/30/2010 to request information from Principal Investigator.    Top of page Randomized, double-blind, vehicle-controlled, multicenter, parallel group study to assess the efficacy, safety, & tolerability of topical terbinafine HCl for 24 or 48 weeks of treatment in patients with mild to moderate toenail onychomycosis   Principal Investigator: Julian Mackay-Wiggan   Start date: 11/15/2006 End date: 05/31/2009 to request information from Principal Investigator.    Top of page Single Center, Open-Label, Efficacy and Safety of Tazarotene for the Treatment of Brittle Nails   Principal Investigator: Richard K. Scher   Start date: 11/12/2004 End date: 05/31/2008 to request information from Principal Investigator.    Top of page Department : Dermatology Division : Other Chemoprevention of Basal Cell Carcinomas with Tazarotene   Principal Investigator: David R. Bickers   Start date: 07/01/2007 End date: 06/30/2008 to request information from Principal Investigator.    Top of page Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of a subcutaneous formulation fo Icatibant for the treatment of Hereditary Angioedema   Principal Investigator: David J Resnick   Website: landerson@inclin.com Start date: 11/01/2005 End date: 05/31/2008 to request information from Principal Investigator.    Top of page Department : Dermatology Division : Pediatrics APPLES - Prospective Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Tacrolimus Ointment for the Treatment of Atopic Dermatitis   Principal Investigator: Kimberly D. Morel   Start date: 11/22/2005 End date: 09/30/2020 to request information from Principal Investigator.    Top of page Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study of the Safety and Efficacy of Thymosin Beta 4 in the Treatment of Patients with Epidermolysis Bullosa   Principal Investigator: Kimberly D. Morel   Start date: 01/19/2006 End date: 07/31/2008 to request information from Principal Investigator.    Top of page Department : Medicine Division : Cardiology ACROSS CYPHER - Approaches to Chronic Occlusions with Sirolimus Stents   Principal Investigator: Jeffrey W. Moses   Start date: 05/09/2005 End date: 11/30/2008 to request information from Principal Investigator.    Top of page ARVD - Multidisciplinary Study of Right Ventricular Dysplasia ARVD study (Yr 1)   Principal Investigator: Hasan Garan   Start date: 08/01/2005 End date: 07/31/2008 to request information from Principal Investigator.    Top of page Angioguard - Carotid Artery Stenting with Embolic Protection Surveillance-Post Marketing Study   Principal Investigator: Issam D. Moussa   Start date: 06/02/2005 End date: 11/30/2008 to request information from Principal Investigator.    Top of page Assessment of Antibodies to Adeno-Associated Vector Type 1 in Patients with Heart Failure   Principal Investigator: Donna Mancini   Start date: 03/08/2007 End date: 09/30/2008 to request information from Principal Investigator.    Top of page CAPTURE 2 - CAPTURE 2: A POST-APPROVAL STUDY OF THE GUIDANT CAROTID STENT SYSTEMS AND EMBOLIC PROTECTION SYSTEMS   Principal Investigator: Issam D. Moussa   Start date: 04/06/2006 End date: 06/30/2008 to request information from Principal Investigator.    Top of page CHAMPION - Clinical Trial Comparing Cangrelor to Clopidogrel in Subjects who Require Percutaneous Coronary Intervention   Principal Investigator: George Dangas   Start date: 04/24/2008 End date: 10/31/2010 to request information from Principal Investigator.    Top of page CHOICE - CHOICE Study - Carotid Stenting For High Surgical-Risk Patients; Evaluating Outcomes Through The Collection Of Clinical Evidence.   Principal Investigator: William Gray   Start date: 02/28/2008 End date: 08/31/2009 to request information from Principal Investigator.    Top of page COSTAR II - Cobalt Chromium Stent with Antiproliferative for Restenosis II Trial   Principal Investigator: Michael Collins   Website: unknown Start date: 06/08/2005 End date: 12/31/2009 to request information from Principal Investigator.    Top of page CUPID Trial - Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease   Principal Investigator: Donna Mancini   Start date: 05/04/2007 End date: 11/30/2012 to request information from Principal Investigator.    Top of page Carotid DVA   Principal Investigator: Issam D. Moussa   Start date: 01/27/2006 End date: 07/31/2009 to request information from Principal Investigator.    Top of page Complete SE Registry - Complete SE Registry: Percutaneous interventional treatment of iliac artery lesions using the Medtronic Complete® Self-Expanding (SE) Iliac Stent.   Principal Investigator: William Gray   Start date: 04/15/2008 End date: 10/31/2010 to request information from Principal Investigator.    Top of page Cryo Cath - Cryocath Frezzor Cryo Ablation Catheter System   Principal Investigator: Hasan Garan   Start date: 02/07/2007 End date: 08/31/2009 to request information from Principal Investigator.    Top of page Double-blind, prospective, randomized, placebo-controlled study to determine the tolerability, efficacy, safety, and dose range of intramyocardial injections of G-CSF mobilized Auto-CD34+ cells for reduction of angina episodes in pts with refractory   Principal Investigator: Warren Sherman   Start date: 08/14/2006 End date: 02/28/2011 to request information from Principal Investigator.    Top of page EMPIRE - Embolic Protection with Reverse Flow Study of the Gore Neuro Protection System in Carotid Stenting of Subjects at High Risk for Carotid Endarterectomy   Principal Investigator: William Gray   Start date: 10/08/2007 End date: 03/31/2010 to request information from Principal Investigator.    Top of page ENDEAVOR 4 - Randomized, controlled trial of the medtronic endeavor drug(ABT-578) eluting coronary stent system vs. the Taxus Paclitaxel-eluting coronary stent system in de novo native coronary lesions   Principal Investigator: Jeffrey W. Moses   Start date: 05/12/2005 End date: 11/30/2010 to request information from Principal Investigator.    Top of page EVEREST I - Study of the EvalveÔ Cardiovascular Valve Repair System (CVRS) Endovascular Valve Edge-to-Edge REpair STudy   Principal Investigator: William Gray   Start date: 04/08/2004 End date: 07/31/2008 to request information from Principal Investigator.    Top of page EVEREST II - Study of the Evalve Cardiovascular Valve repair system (CVRS) endovascular valve edge-to-edge repair study   Principal Investigator: William Gray   Start date: 03/21/2005 End date: 09/30/2009 to request information from Principal Investigator.    Top of page EXACT   Principal Investigator: Issam D. Moussa   Start date: 07/31/2006 End date: 02/28/2009 to request information from Principal Investigator.    Top of page Escape - Effect of Septal Closure of Atrial PFO on Events of Migraine with the Premere Device Escape Migraine Trial   Principal Investigator: Robert Sommer   Start date: 02/13/2006 End date: 08/31/2008 to request information from Principal Investigator.    Top of page Lipoprotein Utilization and Oxidation in CHF   Principal Investigator: Ulrich P Jorde   Start date: 07/01/2007 End date: 06/30/2008 to request information from Principal Investigator.    Top of page MGH OFDI - MGH OFDI: Natural History of Vulnerable Coronary Plaques   Principal Investigator: Martin Leon   Start date: 08/01/2007 End date: 03/31/2009 to request information from Principal Investigator.    Top of page MOMENTUM - Multicenter trial of the Orqis Medical CRS for the Enhanced Treatment of CHF Unresponsive to Medical Therapy   Principal Investigator: Donna Mancini   Start date: 02/24/2006 End date: 08/31/2008 to request information from Principal Investigator.    Top of page MYOHEART - Myogenesis Heart Efficiency and Regeneration Trial   Principal Investigator: Warren Sherman   Start date: 07/11/2006 End date: 01/31/2012 to request information from Principal Investigator.    Top of page MediGuide Trial - MediGuide Trial: Medical Positioning System (MPS) In Conjunction with Guided Measurement Catheter (GMC™) Feasibility Study in Clinical Routine.   Principal Investigator: Giora Weisz   Start date: 03/09/2008 End date: 09/30/2009 to request information from Principal Investigator.    Top of page Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Effects of KW-3902 Injectable Emulsion on Heart Failure Signs and Symptoms, Diuresis, Renal Function, and Clinical Outcomes in Subjects Hospitalized with Worsening Renal Function   Principal Investigator: Paolo C. Colombo   Start date: 12/19/2007 End date: 07/31/2011 to request information from Principal Investigator.    Top of page Multicenter, Single Arm Study of the TAxus Liberte Stent for the Treatment of Patients with DeNovo Coronary Artery Lesions in Small Vessels   Principal Investigator: Donna Mancini   Start date: 08/02/2006 End date: 02/28/2009 to request information from Principal Investigator.    Top of page Optivol Study - Correlation Between T Wave Alternans and Intrathoracic Impedance Measurements Using Optivol T Wave Alternans/Optivol Study.   Principal Investigator: Jose Dizon   Start date: 04/28/2007 End date: 10/31/2010 to request information from Principal Investigator.    Top of page PARTNER - The PARTNER Trial: Placement of Aortic Transcatheter Valves Trial   Principal Investigator: Martin Leon   Start date: 05/29/2007 End date: 11/30/2009 to request information from Principal Investigator.    Top of page PROTECT-II - multicenter, randomized, double-blind, placebo-controlled study of the effects of KW-3902 Injectable Emulsion on heart failure signs and symptoms and renal function in subjects with acute heart failure signs and renal impairment who are hospi   Principal Investigator: Maryjane A. Farr   Start date: 02/14/2008 End date: 09/30/2010 to request information from Principal Investigator.    Top of page Perseus Trial - Perseus Trial: A Prospective Evaluation in a Non-Randomized Trial of the Safety and Efficacy of the Use of the TAXUS[r] ElementTM Paclitaxel-Eluting Coronary Stent System for the Treatment of De Novo Coronary Artery Lesions in Small Vesse   Principal Investigator: Jeffrey W. Moses   Start date: 01/28/2008 End date: 08/31/2013 to request information from Principal Investigator.    Top of page Perseus Workhorse Trial - Perseus WorkhorseTrial: A Prospective Evaluation in a Non-Randomized of the Safety and Efficacy of the Use of the TAXUS (R) ElementTM Paclitaxel-Eluting Coronary Stent System for the Treatment of De Novo Coronary Artery Lesions i   Principal Investigator: Jeffrey W. Moses   Start date: 01/28/2008 End date: 08/31/2013 to request information from Principal Investigator.    Top of page Power Disc-15 - Comparison of Safety and Inhalation Times of Ventavis (iloprost) Inhalation Solution Delivered by I-Neb Utilizing Power Disc-6 and Power Disc-15   Principal Investigator: Evelyn M Horn   Start date: 06/19/2007 End date: 12/31/2009 to request information from Principal Investigator.    Top of page Protect II (IMPELLA) - PROTECT II: A Prospective, multi-center randomized controlled trial of the IMPELLA® RECOVER® LP 2.5 System versus Intra Aortic Balloon Pump (IABP) in Patients Undergoing Non-Emergent High Risk PCI   Principal Investigator: Michael Collins   Start date: 04/10/2008 End date: 10/31/2009 to request information from Principal Investigator.    Top of page RECORDAF - Registry on Cardiac Rhythm Disorders: An International, Observational, Prospective Survey Assessing the Control of Atrial Fibrillation.   Principal Investigator: James A. Reiffel   Start date: 01/16/2008 End date: 07/31/2009